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John Goldman Award

ESH INTERNATIONAL JOHN GOLDMAN RESEARCH AWARD

THE JOHN GOLDMAN 2022 WAS AWARDED TO

Dr. Naranie Shanmuganathan

Royal Adelaide Hospital, Adelaide, Australia

For her two-year project on:
”Comprehensive and sensitive genomic characterisation of diverse mutation types associated with treatment resistance for patients with CML using an RNA-based model”

“My project will hopefully help pave the path for genomic interrogation of CML patients at diagnosis so for the merits of the project to be recognized and awarded the John Goldman prize is a huge honour.
This successful completion of this work will be beyond helpful in aiding
my future research career in haematology.”

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THE JOHN GOLDMAN 2021 WAS AWARDED TO

Dr. Emmanuelle Clappier

Dept. of Haematology, Saint-Louis Hospital, Paris, France

For her two year project on
“Biological significance of BCR-ABL1 clonal hematopoiesis
in Ph-positive acute lymphoblastic leukemia (Ph+ ALL):
relevance for treatment-free remission“

“I am very honored and grateful to receive the 2021 John Goldman Research Award. Our project on Ph+ ALL stems from previous observations of presence of residual, non-lymphoblastic, BCR-ABL1+ cells in patients in continuous complete remission, challenging the significance of BCR-ABL1-based MRD in Ph+ ALL. This support from the European School of Hematology will allow us to develop single-cell omics approaches in order to decipher the clonal architecture of Ph+ ALL, which will impact on therapeutic management of these patients.”

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THE JOHN GOLDMAN 2020 WAS AWARDED TO

Dr. Vaidehi Krishnan

Laboratory of Hematological Malignancies, DUKE-NUS, Singapore

For her two year project on
“High dimensional single cell analysis to predict TFR at the time of CML diagnosis”

“I am honoured and thankful to be chosen as the recipient of the John Goldman Research Award this year.  Our project aims to interrogate diagnostic CML bone marrow samples using the latest single-cell approaches, and identify patients who will have durable treatment free responses. By integrating the results of our analyses with established clinical workflows, we hope to develop a test that can reliably predict the outcome of TKI discontinuation.  This prestigious award from the European School of Haematology offers us the opportunity to leverage cutting-edge technologies toward our long-term goal of developing curative approaches for patients with CML.” 

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THE JOHN GOLDMAN 2019 WAS AWARDED TO

Dr. Ilaria Pagani

Leukaemia Research Group, Cancer Program, SAHMRI, Adelaide, Australia

For her two year project on
“Use of machine learning to integrate clinical data and biomarkers to optimise prediction of TFR”

“It is an honour and a pleasure to be the first John Goldman Research Prize Awardee. Receiving funding support from the European School of Haematology (ESH) is a privilege. It represents a critical step in my career towards becoming an independent investigator and provides the opportunity to build new collaborations. My project aims to identify bioassays that can be integrated with clinical data in a machine learning system to develop a personalized predictive model for treatment free remission (TFR). I expect it will bring novel insights into the biology of TFR, opening new horizons toward the discovery of targeted therapies and improving TFR patient outcome.” 

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ESH extends sincere thanks to the 2019, 2020, 2021 and 2022 Award reviewers: