

ABOUT THE CONFERENCE:
The ESH 4th Translational Research Conference: Chronic Lymphocytic Leukaemia proposes a programme of leading-edge basic and clinical science, as well as opportunities for informal scientific interaction with a panel of global experts in the field.
It is open to an international audience of biologists and clinicians, including those still in-training. This translational research conference will bring together biologists and clinicians with an interest in Chronic Lymphocytic Leukaemia (CLL) in order to explore the most recent advances in the understanding of the pathogenesis and clinical behaviour of the disease.
The presentation of new data is encouraged, as well as spirited debates on how to use this knowledge to the future of CLL therapy.
CONFERENCE MAIN SCIENTIFIC TOPICS:
• Spectrum of CLL - one disease or more
• Richter transformation
• Drivers of disease progression - from genetics, epigenetics, and proteomics (complexity of the evolution)
• The microenvironment of CLL
• Time limited therapies: which combination? which duration? which markers to stop therapy?
• BTK inhibition or degradation?
• The new challenge: resistance to one or two inhibitor classes? - Double refractory CLL
• Future therapies, new compounds
• Directions and strategies to use the best agents in the optimal way: sequencing, combinations, costs of therapy, availability
LEARNING OBJECTIVES
• Understand recent advances in elucidating the pathogenesis of CLL
• Describe recent data on therapeutic regimens for CLL
• Understand emerging data on mechanisms of resistance to targeted agents in CLL
• Understand the debate about how best to optimize CLL therapy in the future
THE PROGRAMME WILL INCLUDE:
Plenary Sessions - Brief Oral Communications - Debates
Roundtables discussions - Panel Discussions - Poster Walks
Meet the Expert Sessions - Ample time for in-depth discussion
Abstracts are eligible for brief oral communications or poster presentations.
Deadline: December 19th, 2025