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Chairs: Dominique Bonnet, Daniela Krause, Simon Méndez-Ferrer
KEYNOTE LECTURE I
The niche concept – Toshio Suda
SESSION I: PATHOBIOLOGY OF THE TUMOUR MICROENVIRONMENT
Tumour microenvironment in MPN – Marie-Caroline Le Bousse-Kerdilès
Effect of aging on tumor microenvironment – Hartmut Geiger
SESSION II: IMAGING OF THE TUMOUR MICROENVIRONMENT
Dynamic interactions between normal and malignant haematopoietic cells and their niches – Cristina Lo Celso
Three dimensional imaging of the bone marrow microenvironment in health and disease – Cesar Nombela-Arrieta
SESSION III: INTERACTION OF TUMOUR CELLS WITH THEIR MICROENVIRONMENT
Ikaros mutation confers stromal dependence and FAK activation in high-risk B-ALL – Rick Van Etten
Regulation of normal and leukaemia human stem cells – Tsvee Lapidot
SESSION IV: SHAPING OF THE TUMOUR MICROENVIRONMENT – VESSELS
The origin of leukaemias in the bone marrow – Juerg Schwaller
SESSION V: SHAPING OF THE TUMOUR MICROENVIRONMENT – STROMAL CELLS
Implanting and reprogramming: Cell-cell communications in B cell malignancies – Ingo Ringshausen
Deconstructing mesenchymal contributions to bone marrow failure and myelodysplasia – Marc Raaijmakers
SESSION VI: IMMUNOLOGICAL ASPECTS AND THE TUMOUR MICROENVIRONMENT
The role of adaptive and innate immunity in the tumour stroma in controlling metastatic disease – Joerg Huelsken
SESSION VII: TUMOUR MICROENVIRONMENT IN LEUKAEMIA, LYMPHOMA AND PLASMA CELL MYELOMA
Effect of microenvironment on myeloma – Irene Ghobrial
Lymphoma – Karin Tarte
SESSION VIII: 3D AND COMPUTER MODELING OF THE TUMOUR MICROENVIRONMENT
A systems biological perspective on stem cell / niche interactions – Ingo Roeder
The microenvironment / niche in human bone marrow and cancer – Paolo Bianco
KEYNOTE LECTURE III
Immunological aspects of the tumour microenvironment – Andreas Diefenbach
SESSION IX: TARGETING OF THE TUMOUR MICROENVIRONMENT / CLINICAL CASE STUDIES
Moving LSC out of the niche – Amnon Peled
Therapeutic targeting of diseased microenvironment in leukaemia: mechanisms and approaches – Marina Konopleva
SESSION X: CASE STUDIES / CLINICAL CORRELATION AND TRANSLATION
Modulation of the bone marrow microenvironment by PTH for improvement of therapy for CML – Daniela Krause
Microenvironment in B cell lymphoma – Jianguo Tao
