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ESH International Conference IMMUNE THROMBOCYTOPENIA

ESH International Conference IMMUNE THROMBOCYTOPENIA
April 30 - May 02, 2010 - Lisbon, Portugal
Chairs :

Information

Immune thrombocytopenia (ITP) is a bleeding disorder characterized by the induction of an autoreactive immune response against one’s own platelets, resulting in increased platelet destruction and reduced megakaryocyte function.  In the last 10 years, many publications have shed new light on several clinical and scientific questions relating to ITP.  It is now clear that ITP may have more than one etiology and is a complex and heterogeneous disorder and new clinical definitions of the disease have arisen.   Perhaps more striking is the rapid evolution of novel therapeutics that have shown great benefit to even the most refractory of patients with ITP and these have been incorporated into new consensus guidelines.  This meeting will bring together many of the world’s leading clinical and scientific experts on ITP and will present a comprehensive program of lectures and posters to summarize the current state-of the-art knowledge and treatments of ITP.

Programme

Friday, April 30, 2010

Morning: Basic Science of ITP - Chair: J. Semple
09h00 - 09h45 Megakaryocyte differentiation and platelet production A. Weyrich (Salt Lake City)
09h45 - 10h30 Autoimmune mechanisms and T regulatory cell disturbances in ITP K. Yazdanbakhsh (New York)
10h30 - 11h00 Coffee break
11h00 - 11h45 Mouse models of ITP J.W. Semple (Toronto)
11h45 - 12h30 Peptide therapy for patients with ITP S. Urbaniak (Aberdeen)
12h30 - 14h00 Lunch
Afternoon: Clinical Dilemmas - Chair: D. Provan
14h00 - 14h45

Pathogenesis of ITP

D. Cines (Philadelphia)
14h45 - 15h30 A patient journey C. Black (London)
15h30 - 16h00 Coffee break
16h00 - 16h45 How useful is the indium labelled platelet survival study? A. Sarpatwari (London)
16h45 - 17h30 Splenectomy – best option for induction of durable remission in chronic ITP? H. Wadenvik (Gothenburg)
19h30 Welcome cocktail
20h00 Dinner

Saturday, May 1, 2010

Morning:

Novel Therapeutics - Chair: D. Kuter

09h00 - 09h45 Thrombopoietin mimetics - old and new

D. Kuter (Boston)

09h45 - 10h30 Clinical studies with TPO mimetics J. Bussel (New York)
10h30 - 11h00 Coffee break
11h00 - 11h45 Anti-CD20 monoclonal antibodies – old and new M. Michel (Créteil)
11h45 - 12h30 Recent advances in Fc receptor-dependant therapies A. Lazarus (Toronto)
12h30 - 14h00 Lunch
Afternoon: Free Communications - Chair: A. Newland

5 short communications:  10 minute-presentation followed by a 5 minute-discussion

Sunday, May 2, 2010

Morning: The Future - Chair: D. Cines
09h00 - 09h45 FC Receptors R. Clynes (New York)
09h45 - 10h30 Regulatory antibodies to apoptotic cell membranes:
Prospects for treatment of autoimmune diseases
G. Silverman (La Jolla)
10h30 - 11h00 Coffee break
11h00 - 11h45 CTL-mediated ITP

B. Olsson (Gothenburg)

11h45 - 12h30 Future Therapies A. Newland (London)
12h30 Light lunch and departure

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