ESH Conference
MYELOPROLIFERATIVE DISORDERS
Chairs: T. Barbui, A.R. Green, H.L. Pahl, R. Skoda, W. Vainchenker
September 18 - 20, 2008, Athens, Greece


 Preliminary Programme


     
Thursday, September 18, 2008
SESSION I Chairman: Tony Green (Cambridge, UK)  
18:00 Myeloproliferative disorders - mutations and mechanisms G. Gilliland (Boston, USA)
18:25 CML stem cells and their clinical relevance C. Eaves (Vancouver, Canada)
18:50 New insights into the relationship between leukocytes and vascular events in essential thrombocythemia T. Babui (Bergamo, Italy)
19:15 JAK2 Inhibitors: Phase 1 Clinical Trials S. Verstovsek (MD Anderson, USA)
19:40 Finish  
20:00 Cocktails and Dinner  

 

Friday, September 19, 2008
SESSION II Chairman: Tiziano Babui (Bergamo, Italy)  
08:30 JACK2V617F and genetic instability W. Vainchenker (Paris, France)
08:55 Modulation of MPD phenotype by transcription factor NF-E2 H. Pahl (Freiburg, Germany)
09:20 Endothelial progenitor cells and angiogenesis in myeloproliferative disorders G. Barosi (Pavia, Italy)
09:45 Short Talk  
10:00 Short Talk  
10:15 Tea  
10:45 Molecular and cellular pathogenesis of the myeloproliferative disorders T. Green (Cambridge, UK)
11:10 Genetics of the myeloproliferative disorders R. Skoda (Basel, Switzerland)
11:35 MPD disease progression: mechanisms and therapy M. Ruben (Mayo Clinic, USA)
12:00 Short Talk  
12:15 Short Talk  
12:30 Lunch & Posters  
SESSION III Chairman: Gary Gilliland (Boston, USA)  
18:00 Molecular and cellular mechanism of primary myelofibrosis R. Hoffman (New York, USA)
18:25 Genomic features of myeloproliferative disorders P. Campbell (Cambridge, UK)
18:50 Familial polycythemia vera and other germline mutations causing polycythemias J. Prchal (Utah, USA)
19:15 short talk  
19:30 Finish  
20:00 Dinner  

 

Saturday, September 20, 2008
SESSION IV Chairman: Heike Pahl (Freiburg, Germany)  
08:30 Phenotype and genotype in the chronic myeloproliferative disorders J. Spivak (Baltimore, USA)
08:55 Aberrant JAK-STAT signaling in myeloproliferative neoplasms S. Constantinescu (Brussels, Belgium)
09:20 Interferon may be effective in the treatment of the cellular phase of primary myelofibrosis and reduces splenomegaly R. Silver (New York, USA)
09:45 Short Talk  
10:00 Short Talk
10:15 Tea  
10:45 Prognostic assessment in primary myelofibrosis F. Cervantes (Barcelona, Spain)
11:10 Epigenetic mechanisms in the pathogenesis of primary myelofibrosis A. Vannucchi (Florence, Italy)
11:35 JAK2 (V617F) allele burden, phenotype, and clinical course of myeloproliferative disorders M. Cazzola (Pavia, Italy)
12:00 Short Talk
12:15 Lunch & Posters  
SESSION V Chairman: Radek Skoda (Basel, Switzerland)  
14:00 Atypical myeloproliferative disorders: pathogenesis and therapy N. Cross (Salisbury, UK)
14:25 Staging and prognosis in primary myelofibrosis (PMF) M. Kvasnicka (Cologne, Germany)
14:50 Novel molecular targets and targeted therapies in the myeloproliferative disorders R. Van Etten (Boston, USA)
13:15 Short Talk  
15:30 Tea  
16:00 Role of tumor necrosis factor-alpha in murine JAK2 V617F-positive myeloproliferative disorders M. Deininger (Portland, USA)
16:25 Mechanisms of thrombosis in myeloproliferative disorders B. Furie (Boston, USA)
16:50 The apoptotic response to kinase inhibition in myeloproliferative disorder D. Tenen (Boston, USA)
17:15 Manned Poster Session with refreshments  
18:30 Finish  
20:00 Conference Dinner