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Thursday, October 16 |
| 12:00 |
Registration |
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| Session 1 |
Cord blood transplant: banking, organization, regulatory issues
Chair: P. Wernet, P. Rubinstein |
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| 14.00-14.15 |
Netcord organization |
J. Garcia (Barcelona) |
| 14.15-14.30 |
Challenges in the international exchange of CBUs |
M. Boo (Minneapolis) |
| 14.30-14.45 |
Biological resource center |
P. Rebulla (Milan) |
| 14.45-15.00 |
Report from Japan and Asia |
S. Kato (Isehara) |
| 15.00-15.15 |
Latin America |
E. Calderon (Mexico City) |
| 15.15-15.30 |
London cord blood bank |
C. Navarrete (London) |
| 15.30 - 16.00 |
Coffee-Break |
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| 16.00-16.30 |
Sibling cord blood banking |
B. Lubin (Oakland) |
| 16.30-17.00 |
The unrealized potential of umbilical cord blood units for unrelated donor hematopoietic cell transplantation. |
L. Petz (Arcadia) |
| 17.00-18.00 |
Debate: Is there a place for autologous cord blood banking? |
L. Petz (Arcadia)
G. Garrido (Madrid)
Y. Beguin (Liège) |
| 19.00 |
Opening Ceremony Celebration Cord Blood Transplant History
Guest of Honour: Emmanuelle PRADA BORDENAVE Director General of the French National Biomedical Agency (directrice générale de l'Agence de la biomédecine)
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Special Guests:
A. Auerbach (New York)
M. Benbunan (Paris)
H. Broxmeyer (Indianapolis)
M. Contreras (London)
E. Gluckman (Paris)
J. Kurtzberg (Durham),
P. Rubinstein (New York)
G. Sirchia (Milan)
J.J. Van Rood (Leiden)
J. Wagner (Minneapolis)
P. Wernet (Dusseldorf)
and Patients |
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Friday, October 17 |
| Session 2 |
Stem cells from cord blood – Chair: W. Fibbe, P. Simmons |
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| 9.00-9.30 |
Cord blood-derived very small embryonic like (VSEL) stem cells |
M. Ratajczak (Louisville) |
| 9.30-10.00 |
Biology of cord blood stem cells |
P. Simmons (Houston) |
| 10.00-10.30 |
Functional characterization of stem cell subpopulations in cord blood |
G. Kögler (Düsseldorf) |
| 10.30-11.00 |
Coffee-Break |
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| 11.00-11.30 |
Embryonic like cells from umbilical cord blood |
C. McGuckin (Newcastle) |
| 11.30-12.00 |
The umbilical cord as a stem cell source: cells derived from Wharton's Jelly |
M.L. Weiss (Manhatten) |
| 12.00-12.30 |
Notch signalling in haematopoietic stem cell differentiation: implications for cord blood transplantation |
I. Bernstein (Seattle) |
| 12.30-13.00 |
Mesenchymal stem cells: Role in cord blood transplantation |
W. Fibbe (Leiden) |
| 13.00-14.00 |
Buffet lunch and poster viewing |
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| Session 3 |
The role of the hematopoietic microenvironment on hematopoietic stem cell function
Chair: H.E.Broxmeyer, G. Kögler |
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| 14.00-14.30 |
Re-defining human circulating endothelial progenitor cells |
M.C. Yoder (Indianapolis) |
| 14.30-15.00 |
Early foetal MSC and maternal and foetal tissue repair |
N.M. Fisk (Brisbane) |
| 15.00-15.30 |
USSC from Cord Blood as Neuronal Progenitors and their Strong Tropism for Neuronal Injury Areas |
P. Wernet (Düsseldorf) |
| 15.30-16.00 |
Cord blood to treat neurological diseases |
J. Kurtzberg (Durham) |
| 16.00-16.30 |
Coffee-break and poster viewing |
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| 16.30-17.00 |
Isolation and characterization of cells from human term placenta |
O. Parolini (Brescia) |
| 17.00-17.30 |
Stem cells and microenvironment |
J.A. Cancelas (Cincinnati) |
| 17.30-18.00 |
Resetting the immune-clock: Stemcellness vs.diversity |
D. Charron (Paris) |
| 18.00-18.30 |
Discussion |
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Saturday, October 18 |
| Session 4 |
Immunological properties – Chair: D. Charron, J.J. Van Rood |
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| 8.00-8.30 |
Umbilical cord blood-derived T cells expressing chimeric antigen receptor to target B-cell malignancies |
P. Dotti (Houston) |
| 8.30-9.00 |
Immune properties of cord blood |
F. Falkengurg (Leiden) |
| 9.00-9.30 |
Virus specific cord blood T cells for clinical use |
C. Bollard (Houston) |
| 9.30-10.00 |
Natural killer cells in cord blood and stem cell transplantation |
R. Champlin (Houston) |
| 10.00-10.30 |
Coffee-Break |
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| Session 5 |
Role of HLA in cord blood transplant – Chair: J. Wagner, V. Rocha |
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| 10.30-11.00 |
Influence of KIR mismatching in the outcome of cord blood transplant |
R. Willemze (Leiden) |
| 11.00-11.30 |
Role of HLA and cell dose in cord blood transplant |
P. Rubinstein (New York) |
| 11.30-12.30 |
Panel discussion on donor choice |
J. Wagner (Minneapolis)
P. Rubinstein (New York)
E. Gluckman (Paris)
M. Eapen (Milwaukee) |
| 12.30 - 13.30 |
Lunch |
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| Session 6 |
Clinical results in adults - R. Champlin, J. Barker |
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| 13.30-14.00 |
Cord Blood or non T-cell depleted Haploidentical Transplant for Patients with Haematological Malignancies |
A. Picardi (Rome) |
| 14.00-14.30 |
Acute leukaemia |
V. Rocha (Paris) |
| 14.30-15.00 |
Double cord blood transplant |
J. Wagner (Minneapolis) |
| Session 7 |
Cord blood transplant in children - Chair: J. Kurtzberg, F. Locatelli |
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| 15.00-15.30 |
Hurler |
J. Boelens (Utrecht) |
| 15.30-16.00 |
Leukaemia |
F. Locatelli (Pavia) |
| 16.00-16.30 |
Haemoglobinopathies |
M. Walters (Oakland) |
| 16.30-17.00 |
Coffee-Break |
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| 17.00-18.30 |
Selected abstracts and poster presentation - E.J. Shpall, E. Gluckman, J. Garcia |
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Sunday, October 19 |
| Session 8 |
Graft facilitation-Homing – Chair: F. Frassoni, T. Lapidot |
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| 8.30-9.00 |
Mechanistic insights into engraftment |
H.E. Broxmeyer (Indianapolis) |
| 9.00-9.30 |
Dynamic intercations between the nervous and immune systems with microenvironment regulate hematopoietic stem cells |
T. Lapidot (Rehovot) |
| 9.30-10.00 |
Stem cells and their niche: a leverage point for therapy |
D. Scadden (Boston) |
| 10.00-10.30 |
Methods for promoting engraftment |
E.J. Shpall (Houston) |
| 10.30-11.00 |
Coffee-Break |
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| Session 9 |
New protocols for cord blood transplant - Chair: E. Gluckman, M. Eapen |
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| 11.00-11.30 |
Lymphoma |
C. A. Rodrigues (São Paulo) |
| 11.30-12.00 |
Reduced intensity conditioning |
J. Barker (New York) |
| 12.00-12.30 |
Direct intra-bone (IBM) transplant of cord blood cells |
F. Frassoni (Genoa) |
| 12.30-13.00 |
Discussion |
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