|
|
| Friday, October 3 |
| 13:00 - 14:00 |
Welcome Lunch Buffet |
|
| 14:00 - 14:15 |
Welcome: Purpose of Meeting |
B. Löwenberg, H. Döhner |
| 14:15 - 16:30 |
Session 1 - Gene Mutations (I) - Chair: H. Dombret |
|
| 14:15 - 14:35 |
NPM1:
Biology and prognostic significance |
B.
Falini |
| 14:35 - 14:50 |
NPM1:
Prognostic significance |
K.
Döhner |
| 14:50 - 15:05 |
NPM1:
Therapeutic targeting |
R.
Schlenk |
| 15:05 - 15:20 |
FLT3:
Prognostic significance |
R.
Gale |
| 15:20 - 15:35 |
FLT3:
Prognostic significance: allelic ratio |
C.
Thiede |
| 15:35 - 15:50 |
FLT3:
Therapeutic targeting |
D.
Small |
| 15:50 - 16:30 |
Round Table |
|
| 16:30 - 17:00 |
Coffee break |
|
| 17:00 - 19:15 |
Session 2 - Gene
Mutations (II) - Chair: C. Bloomfield |
|
| 17:00 - 17:15 |
CEBPA: Biology and prognostic significance |
H. Dombret |
| 17:15 - 17:30 |
CEBPA: Familial AML |
T. Pabst |
| 17:30 - 17:45 |
KIT: Prognostic significance |
P. Paschka |
| 17:45 - 18:00 |
WT1: Prognostic significance |
J. Fitzgibbon |
| 18:00 - 18:15 |
MLL: Biology and prognostic significance |
S.
Whitman |
| 18:15 - 18:30 |
AML1: Biology and relation to cytogenetics |
S.
Schnittger |
| 18:30 - 19:15 |
Round Table |
|
| Saturday, October 4 |
| 08:30 - 10:00 |
Session 3 - Prognostic Impact of
Cytogenetics: New Insights Revisited - Chair: J. Sierra |
|
| 08:30 - 08:50 |
Individual
cytogenetic markers |
C.
Bloomfield |
| 08:50 - 09:10 |
Individual
cytogenetic markers |
B.
Löwenberg |
| 09:10 - 09:30 |
Individual
cytogenetic markers |
D.
Grimwade |
| 09:30 - 10:00 |
Round Table |
|
| 10:00 - 10:30 |
Coffee break |
|
| 10:30 - 12:15 |
Session 4 - Gene Expression - Chair: D. Grimwade |
|
| 10:30 - 10:45 |
BAALC:
Biology and prognostic significance |
C.
Baldus |
| 10:45 - 11:00 |
EVI-1:
Biology and prognostic significance |
R.
Delwel |
| 11:00 - 11:15 |
ERG:
Biology and prognostic significance |
G. Marcucci |
| 11:15 - 11:30 |
MN1:
Biology and prognostic significance |
A.
Ganser |
| 11:30 - 12:15 |
Round Table |
|
| 12:15 - 14:00 |
Lunch |
|
| 14:00 - 16:15 |
Session 5 - Modern Genomics Technologies (I) - Chair: B. Ebert |
|
| 14:00 - 14:20 |
SNP in Pediatric AML |
J. Downing |
| 14:20 - 14:40 |
SNP in Adult AML |
B. Young |
| 14:40 - 14:55 |
Gene
expression profilling |
P. Valk |
| 14:55 - 15:10 |
Gene
expression profilling |
L. Bullinger |
| 15:10 - 15:25 |
Gene
expression profilling |
T. Haferlach |
| 15:25 - 15:40 |
Gene
expression profilling |
M. Radmacher |
| 15:40 - 16:15 |
Round Table |
|
| 16:15 - 16:45 |
Coffee break |
|
| 16:45 - 18:45 |
Session 6 - Modern Genomics Technologies (II) - J. Downing |
|
| 16:45 - 17:05 |
MicroRNA
profiling |
G. Marcucci |
| 17:05 - 17:25 |
MicroRNA
profiling |
M. Jongen |
| 17:25 - 17:45 |
Functional genomics screen |
B. Ebert |
| 17:45 - 18:05 |
Epigenetic profiling |
C. Plass |
| 18:05 - 18:45 |
Round Table |
|
| Sunday, October 5 |
| 08:30 - 11:15 |
Session 7 - Towards
an Integrated Prognostic Algorithm - Chairs: E. Estey and A. Burnett |
|
| 08:30 - 08:45 |
Considerations
about a composite prognostic score |
TBA |
| 08:45 - 09:00 |
Considerations
about a composite prognostic score |
C.
Bloomfield |
| 09:00 - 09:15 |
Considerations
about a composite prognostic score |
A.
Burnett |
| 09:15 - 09:30 |
Considerations
about a composite prognostic score |
H.
Döhner |
| 09:30 - 09:45 |
Considerations
about a composite prognostic score |
H.
Dombret |
| 09:45 - 10:00 |
Considerations
about a composite prognostic score |
E.
Estey |
| 10:00 - 10:30 |
Coffee break |
|
| 10:30 - 10:45 |
Considerations
about a composite prognostic score |
B.
Löwenberg |
| 10:45 - 11:00 |
Considerations
about a composite prognostic score |
J.
Sierra |
| 11:00 - 11:15 |
Considerations
about a composite prognostic score |
M.
Tallman |
| 11:15 - 12:00 |
Session 8 - Open Forum - Chairs: H. Döhner and B. Löwenberg
Final Discussion, Conclusions, Recommendations |
|
| 12:00 - 13:30 |
Farewell lunch |
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