ESH, Eurocord, Netcord, EBMT, UT MD Anderson Cancer Center
Biology and Clinical Applications of Cord Blood Cells 

Chairs: W.E. Fibbe, E. Gluckman, G. Kögler, E.J. Shpall
October 19-21, 2007 - Maison de la Chimie, Paris, France

 


 

Programme

 
 FRIDAY, OCTOBER 19, 2007  
 8.00-9.00 Registration  
 Session 1 : Stem cells  from cord blood - Chair: G. Kögler  
 09.00-09.30 Cord blood-derived very small embryonic like (VSEL) stem cells M. Ratajczak (USA)
 09.30-10.00 Early events in hematopoietic stem cell development E. Dzierzak (Netherlands)
 10.00-10.30 Functional characterization of stem cell subpopulations in cord blood G. Kögler (Germany)
 10.30-11.00 Coffee Break  
 11.00-11.30 Mesenchymal stem cells are derived from a subset of perivascular cells present in all human tissues B. Péault (USA)
 11.30-12.00 Hemopoietic stem cell generation in the mouse embryo  A. Cumano (France)
 12.00-12.30 Notch signaling  in hematopoietic stem cell differentiation:
implications for cord blood transplantation 
I. Bernstein (USA)
 12.30-13.30 Buffet Lunch and poster viewing  
 Session 2 : Mesenchymal cells - Chair: E. J. Shpall  
 13.30-14.00 The mesenchymal paradigm W.E. Fibbe (Netherlands)
 14.00-14.30 Early fetal MSC and maternal and fetal tissue repair N.M. Fisk (UK)
Session 3 : Non hemopoietic stem cells - Chair: D. Scadden  
 14.30-15.00 Tissue regeneration potential in human umbilical cord blood A. Nagler (Israel)
 15.00-15.30 Circulating endothelial progenitor cells: potential cell therapy product and value as biological marker in diseases involving angiogenesis G. Uzan (France)
 15.30-16.00 Therapeutic potential of epidermal stem cells derived from both embryonic and somatic tissues D. Aberdam (France)
 16.00-16.30 Non hematopoietic human umbilical cord blood stem cell line differentiating into neural lineages L. Buzanska (Poland)
 16.30-17.00 Coffee Break  
 17.00-17.30 The umbilical cord as a stem cell source : cells derived from Wharton's Jelly M.L. Weiss (USA)
 17.30-18.00 Re-defining human circulating endothelial progenitor cells M.C. Yoder (USA)
 18.00-18.30 Conditional interference with T-cell and dendritic cell responses of cord blood derived Unrestricted Somatic Stem Cells (USSC) P. Wernet (Germany)
     
SATURDAY, OCTOBER 20, 2007  
Session 4 : Immunological properties - Chair: E. Gluckman  
 08.30-08.50 Umbilical cord blood-derived T cells expressing chimeric antigen receptor to target B-cell malignancies L. Cooper (USA)
 08.50-09.10 Immune reconstitution of cord blood recipients K. Komanduri (USA)
 09.10-09.30 Graft versus host disease of cord blood transplant patients D. Couriel (USA)
Session 5 : Clinical results - Chair: J. Wagner  
 09.30-09.50 Role of HLA and cell dose in cord blood transplant E. Gluckman (France)
 09.50-10.10 Nonmyeloablative stem cell transplantation R. Champlin (USA)
 10.10-10.30 Double versus expanded cord blood transplant: a prospective, randomized trial  M. de Lima (USA)
 10.30-11.00 Coffee Break  
 11.00-11.20 Unrelated cord blood transplants in hereditary disorders J. Kurtzberg (USA)
 11.20-11.40 Cord blood transplantation in adults J. Wagner (USA)
 11.40-12.00 CIBMTR comparisons of cord blood and bone marrow transplantation M. Horowitz (USA)
 12.00-12.20 Comparison of cord blood transplant to other sources of cells  V. Rocha (France)
 12.20-12.45 Discussion  
 12.45-14.00 Lunch  
 14.00-14.20 Cord blood transplants in children F. Locatelli (Italy)
 14.20-14.40 Cord blood transplant in adults with AML W. Arcese (Italy)
 14.40-15.00 Prognostic factors after UCB transplants in adults with hematologic malignancies:
Are the currently accepted guidelines for selecting the best UCB unit adequate?
G. Sanz (Spain)
 15.00-15.20 Structure of data collection M. Horowitz (USA) & F. Garnier (France)
 15.20-15:35 Results of a meta analysis of CIBMTR, NCBP and Eurocord Y. Cohen (Israel)
 15.20-15.50 Discussion  
Session 6 : Ex vivo expansion - Chair: H.E. Broxmeyer   
 15.50-16.10 The multifaceted sides of cord blood expansion W. Piacibello (Italy)
 16.10-16.30 Copper chelator and other technologies for cord expansion E.J. Shpall (USA)
 16.30-16.50 Ex vivo expansion of cord blood cell I. McNiece (USA)
 16.50-17.10 Coffee Break   
 17.10-18.10 Selected abstracts and poster presentation  
  Characterization of mesenchymal stromal cells derived from umbilical cord C. Navarrete et al (UK)
     
SUNDAY, OCTOBER 21, 2007  
Session 7 : Graft facilitation / Homing - Chair: W.E. Fibbe  
 08.30-09.00 Mechanistic insights into engraftment H.E. Broxmeyer (USA)
 09.00-09.30 Regulation of stem cell homing, retention and mobilization T. Lapidot (Israel)
 09.30-10.00 Stem cells and their niche: a leverage point for therapy D. Scadden (USA)
 10.00-10.30 Regulation of self-renewing divisions of HSC by human mesenchymal stroma cells - Clinical consequences A. Ho (Germany)
 10.30-11.00 Direct intra-bone (IBM) transplant of cord blood cells F. Frassoni (Italy)
 11.00-11.30 Coffee Break  
Session 8 : Cord blood transplant: banking, organization, regulatory issues - Chair:  TBA  
 11.30-11.45 Netcord organization J. Garcia (Spain)
 11.45-12.00 Establishing a National Cord Blood Program, the United States Experience M. Boo (USA)
 12.00-12.15 Biological resource center P. Rebulla (Italy)
 12.15-12.30

Development of cord blood banking and transplantation in Asia; Report from Asia Cord

T. Takahashi (Japan)
 12.30-12.40 London cord blood bank C. Navarrete (UK)
 12.40-12.50 Sibling cord blood banking and transplantation B. Lubin (USA)
 12.50-13.00 Autologous cord blood banking: a need or an illusion? Y. Beguin (Belgium)
 13.00-13.10 Economic models of cord blood banks G. Katz Benichou (France)
 13.10-13.30 Discussion  
 13.30 End of the meeting